{"id":3201,"date":"2025-01-24T11:20:50","date_gmt":"2025-01-24T04:20:50","guid":{"rendered":"https:\/\/hienbacsi.com\/?p=3201"},"modified":"2025-01-24T11:21:04","modified_gmt":"2025-01-24T04:21:04","slug":"nhung-thanh-tuu-moi-trong-dieu-tri-viem-gan-b-dang-tren-nejm","status":"publish","type":"post","link":"https:\/\/hienbacsi.com\/index.php\/2025\/01\/24\/nhung-thanh-tuu-moi-trong-dieu-tri-viem-gan-b-dang-tren-nejm\/","title":{"rendered":"Nh\u1eefng th\u00e0nh t\u1ef1u m\u1edbi trong \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B \u0111\u0103ng tr\u00ean NEjM"},"content":{"rendered":"\n<p>Nh\u1eefng th\u00e0nh t\u1ef1u m\u1edbi c\u1ee7a \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B c\u00f3 th\u1ec3 t\u00edch h\u1ee3p c\u00f9ng nhau \u0111\u01b0\u1ee3c \u0111\u0103ng tr\u00ean NEJM c\u00e1ch \u0111\u00e2y m\u1ea5y ng\u00e0y, bs Hi\u1ec1n \u0111\u00e3 \u1ee9ng d\u1ee5ng 1 v\u00e0i th\u00e0nh t\u1ef1u n\u00e0y cho b\u1ec7nh nh\u00e2n \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1ee9ng d\u1ee5ng li\u1ec7u ph\u00e1p t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch t\u1eeb Nh\u1eadt B\u1ea3n cho b\u1ec7nh nh\u00e2n vi\u00eam gan B. Bs chuy\u00ean khoa gan b\u1eaft bu\u1ed9c ph\u1ea3i n\u1eb1m l\u00f2ng h\u00ecnh n\u00e0y, xin c\u1eaft ngh\u0129a c\u00e1c li\u1ec7u ph\u00e1p ph\u1ee9c t\u1ea1p n\u00e0y b\u1eb1ng ng\u00f4n ng\u1eef b\u00ecnh d\u00e2n:<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"590\" height=\"739\" src=\"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5619-1.jpg\" alt=\"\" class=\"wp-image-3199\" srcset=\"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5619-1.jpg 590w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5619-1-240x300.jpg 240w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5619-1-585x733.jpg 585w\" sizes=\"(max-width: 590px) 100vw, 590px\" \/><\/figure>\n\n\n\n<p>Thu\u1ed1c kh\u00e1ng virus: C\u00e1c lo\u1ea1i thu\u1ed1c nh\u01b0 nucleoside ho\u1eb7c nucleotide ng\u0103n ch\u1eb7n virus HBV nh\u00e2n l\u00ean b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzyme polymerase.<\/p>\n\n\n\n<p>Xalnesiran: \u0110\u00e2y l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c gi\u00fap \u1ee9c ch\u1ebf gen c\u1ee7a virus, l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng virus t\u1ea1o ra c\u00e1c th\u00e0nh ph\u1ea7n c\u1ea7n thi\u1ebft \u0111\u1ec3 t\u1ed3n t\u1ea1i v\u00e0 ph\u00e1t tri\u1ec3n.<\/p>\n\n\n\n<p>Ruzotolimod: Thu\u1ed1c n\u00e0y k\u00edch ho\u1ea1t h\u1ec7 mi\u1ec5n d\u1ecbch, gi\u00fap c\u01a1 th\u1ec3 t\u1ea1o ra interferon &#8211; m\u1ed9t lo\u1ea1i protein c\u00f3 kh\u1ea3 n\u0103ng ch\u1ed1ng virus.<\/p>\n\n\n\n<p>Interferon:<br \/>C\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u01a1 th\u1ec3 s\u1ea3n xu\u1ea5t t\u1ef1 nhi\u00ean ho\u1eb7c ti\u00eam t\u1eeb b\u00ean ngo\u00e0i.<br \/>Gi\u00fap t\u0103ng s\u1ee9c m\u1ea1nh c\u1ee7a h\u1ec7 mi\u1ec5n d\u1ecbch, ph\u00e1 h\u1ee7y t\u1ebf b\u00e0o gan b\u1ecb nhi\u1ec5m virus v\u00e0 ng\u0103n virus nh\u00e2n l\u00ean.<\/p>\n\n\n\n<p>T\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch: C\u00e1c t\u1ebf b\u00e0o nh\u01b0 t\u1ebf b\u00e0o T, t\u1ebf b\u00e0o NK, v\u00e0 t\u1ebf b\u00e0o tua (dendritic cells) \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t \u0111\u1ec3 ti\u00eau di\u1ec7t t\u1ebf b\u00e0o nhi\u1ec5m virus v\u00e0 h\u1ed7 tr\u1ee3 c\u01a1 th\u1ec3 ch\u1ed1ng l\u1ea1i HBV.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-768x1024.jpg\" alt=\"\" class=\"wp-image-3200\" srcset=\"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-768x1024.jpg 768w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-225x300.jpg 225w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-1152x1536.jpg 1152w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-1170x1560.jpg 1170w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223-585x780.jpg 585w, https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223.jpg 1500w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><figcaption class=\"wp-element-caption\">ThS BS Tr\u1ea7n H\u1eefu Hi\u1ec1n v\u00e0 b\u1ec7nh nh\u00e2n vi\u00eam gan B bi\u1ebfn ch\u1ee9ng ung th\u01b0 gan<\/figcaption><\/figure>\n\n\n\n<h1 class=\"wp-block-heading\">bacsitranhuuhien #viemganb<\/h1>\n","protected":false},"excerpt":{"rendered":"<p>Nh\u1eefng th\u00e0nh t\u1ef1u m\u1edbi c\u1ee7a \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B c\u00f3 th\u1ec3 t\u00edch h\u1ee3p c\u00f9ng nhau \u0111\u01b0\u1ee3c \u0111\u0103ng tr\u00ean NEJM c\u00e1ch \u0111\u00e2y m\u1ea5y ng\u00e0y, bs Hi\u1ec1n \u0111\u00e3 \u1ee9ng d\u1ee5ng 1&hellip;<\/p>\n","protected":false},"author":1,"featured_media":3200,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[131],"tags":[67,84,53],"jetpack_featured_media_url":"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/01\/img_5223.jpg","_links":{"self":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3201"}],"collection":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/comments?post=3201"}],"version-history":[{"count":2,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3201\/revisions"}],"predecessor-version":[{"id":3203,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3201\/revisions\/3203"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/media\/3200"}],"wp:attachment":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/media?parent=3201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/categories?post=3201"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/tags?post=3201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}