{"id":3359,"date":"2025-08-16T22:09:31","date_gmt":"2025-08-16T15:09:31","guid":{"rendered":"https:\/\/hienbacsi.com\/?p=3359"},"modified":"2025-08-16T22:09:31","modified_gmt":"2025-08-16T15:09:31","slug":"10-nguyen-nhan-gay-tang-men-gan-co-the-phong-ngua","status":"publish","type":"post","link":"https:\/\/hienbacsi.com\/index.php\/2025\/08\/16\/10-nguyen-nhan-gay-tang-men-gan-co-the-phong-ngua\/","title":{"rendered":"10 nguy\u00ean nh\u00e2n g\u00e2y t\u0103ng men gan c\u00f3 th\u1ec3 ph\u00f2ng ng\u1eeba"},"content":{"rendered":"\n

\ud83d\udc68\u200d\u2695\ufe0f ThS.BS Tr\u1ea7n H\u1eefu Hi\u1ec1n<\/strong><\/mark><\/p>\n\n\n\n

\u2022 T\u1ed1t nghi\u1ec7p b\u1eb1ng DIU \u0110\u1ea1i h\u1ecdc Corse \u2013 C\u1ed9ng h\u00f2a Ph\u00e1p<\/p>\n\n\n\n

– Tu nghi\u1ec7p t\u1ea1i b\u1ec7nh vi\u1ec7n King\u2019s College Hospital Lu\u00e2n \u0110\u00f4n Anh Qu\u1ed1c<\/p>\n\n\n\n

\u2022 Th\u00e0nh vi\u00ean H\u1ed9i Nghi\u00ean C\u1ee9u Gan Ch\u00e2u \u00c2u (EASL)<\/p>\n\n\n\n

Trong th\u1eddi gian tu nghi\u1ec7p t\u1ea1i Lu\u00e2n \u0110\u00f4n v\u00e0 qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb cho nhi\u1ec1u b\u1ec7nh nh\u00e2n t\u0103ng men gan, x\u01a1 gan v\u00e0 ung th\u01b0 gan. BS Hi\u1ec1n \u0111\u00e3 \u0111\u00fac k\u1ebft \u0111\u01b0\u1ee3c 10 nguy\u00ean nh\u00e2n g\u00e2y t\u0103ng men gan c\u00f3 th\u1ec3 ph\u00f2ng tr\u00e1nh \u0111\u01b0\u1ee3c:<\/p>\n\n\n\n

ThS BS Hi\u1ec1n trong chuy\u1ebfn \u0111i tu nghi\u1ec7p t\u1ea1i b\u1ec7nh vi\u1ec7n King\u2019s College Hospital<\/figcaption><\/figure>\n\n\n\n

1.        Ti\u00eau th\u1ee5 r\u01b0\u1ee3u qu\u00e1 m\u1ee9c: R\u01b0\u1ee3u l\u00e0 k\u1ebb th\u00f9 th\u1ea7m l\u1eb7ng c\u1ee7a gan, g\u00e2y ra t\u00ecnh tr\u1ea1ng vi\u00eam v\u00e0 t\u00edch t\u1ee5 ch\u1ea5t b\u00e9o, d\u1eabn \u0111\u1ebfn t\u0103ng men gan v\u00e0 ti\u1ebfn tri\u1ec3n th\u00e0nh x\u01a1 gan n\u1ebfu k\u00e9o d\u00e0i. C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y, r\u01b0\u1ee3u l\u00e0 nguy\u00ean nh\u00e2n h\u00e0ng \u0111\u1ea7u g\u00e2y b\u1ec7nh gan \u1edf Anh, v\u1edbi h\u01a1n 1,9 tri\u1ec7u ng\u01b0\u1eddi u\u1ed1ng \u1edf m\u1ee9c h\u1ea1i, l\u00e0m t\u0103ng g\u00e1nh n\u1eb7ng b\u1ec7nh t\u1eadt to\u00e0n c\u1ea7u. H\u01a1n n\u1eefa, ph\u00e2n t\u00edch to\u00e0n c\u1ea7u v\u1ec1 g\u00e1nh n\u1eb7ng x\u01a1 gan ch\u1ec9 ra r\u1eb1ng r\u01b0\u1ee3u chi\u1ebfm t\u1ef7 l\u1ec7 l\u1edbn trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 ph\u00f2ng ng\u1eeba th\u00f4ng qua gi\u00e1o d\u1ee5c v\u00e0 ch\u00ednh s\u00e1ch h\u1ea1n ch\u1ebf. <\/p>\n\n\n\n

2.        B\u00e9o ph\u00ec v\u00e0 h\u1ed9i ch\u1ee9ng chuy\u1ec3n h\u00f3a: B\u00e9o ph\u00ec kh\u00f4ng ch\u1ec9 l\u00e0 v\u1ea5n \u0111\u1ec1 th\u1ea9m m\u1ef9 m\u00e0 l\u00e0 m\u1ed9t \u0111\u1ea1i d\u1ecbch \u00e2m th\u1ea7m t\u1ea5n c\u00f4ng gan, g\u00e2y t\u00edch t\u1ee5 m\u1ee1 d\u1eabn \u0111\u1ebfn b\u1ec7nh gan nhi\u1ec5m m\u1ee1 kh\u00f4ng do r\u01b0\u1ee3u (NAFLD), l\u00e0m t\u0103ng men gan l\u00ean g\u1ea5p \u0111\u00f4i ho\u1eb7c h\u01a1n. V\u1edbi kinh nghi\u1ec7m c\u1ee7a t\u00f4i, vi\u1ec7c gi\u1ea3m c\u00e2n 5-10% tr\u1ecdng l\u01b0\u1ee3ng c\u01a1 th\u1ec3 c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c t\u00ecnh tr\u1ea1ng n\u00e0y, nh\u1ea5n m\u1ea1nh vai tr\u00f2 c\u1ee7a ch\u1ebf \u0111\u1ed9 \u0103n c\u00e2n b\u1eb1ng v\u00e0 t\u1eadp luy\u1ec7n. Nghi\u00ean c\u1ee9u ch\u1ec9 ra r\u1eb1ng s\u1ef1 thi\u1ebfu h\u1ee5t JNK1 \u1edf t\u1ebf b\u00e0o gan c\u00f3 th\u1ec3 ng\u0103n ng\u1eeba t\u00edch t\u1ee5 m\u1ee1, nh\u01b0ng b\u00e9o ph\u00ec l\u00e0m tr\u1ea7m tr\u1ecdng h\u00f3a insulin resistance, t\u0103ng nguy c\u01a1. Ngo\u00e0i ra, s\u1ef1 gia t\u0103ng b\u00e9o ph\u00ec \u1edf th\u1ebf h\u1ec7 tr\u1ebb \u0111ang l\u00e0m tr\u1ea7m tr\u1ecdng h\u00f3a b\u1ec7nh gan, \u0111\u00f2i h\u1ecfi can thi\u1ec7p s\u1edbm \u0111\u1ec3 b\u1ea3o v\u1ec7 th\u1ebf h\u1ec7 t\u01b0\u01a1ng lai. <\/p>\n\n\n\n

3.        Ch\u1ebf \u0111\u1ed9 \u0103n gi\u00e0u ch\u1ea5t b\u00e9o v\u00e0 \u0111\u01b0\u1eddng: M\u1ed9t ch\u1ebf \u0111\u1ed9 \u0103n th\u1eeba calo t\u1eeb ch\u1ea5t b\u00e9o b\u00e3o h\u00f2a v\u00e0 \u0111\u01b0\u1eddng fructose kh\u00f4ng ch\u1ec9 nu\u00f4i d\u01b0\u1ee1ng b\u00e9o ph\u00ec m\u00e0 c\u00f2n tr\u1ef1c ti\u1ebfp g\u00e2y vi\u00eam gan, t\u0103ng men gan th\u00f4ng qua c\u01a1 ch\u1ebf t\u00edch t\u1ee5 lipid. T\u00f4i th\u01b0\u1eddng khuy\u00ean b\u1ec7nh nh\u00e2n r\u1eb1ng: h\u1ea1n ch\u1ebf ch\u1ebf \u0111\u1ed9 \u0103n gi\u1ea3m \u0111\u01b0\u1eddng h\u1ea5p thu nhanh, v\u00ec gan kh\u00f4ng ph\u1ea3i l\u00e0 kho ch\u1ee9a v\u00f4 h\u1ea1n. <\/p>\n\n\n\n

ThS BS Hi\u1ec1n trong chuy\u1ebfn \u0111i tu nghi\u1ec7p t\u1ea1i b\u1ec7nh vi\u1ec7n King\u2019s College Hospital<\/mark><\/strong><\/figcaption><\/figure>\n\n\n\n

4.        Qu\u00e1 li\u1ec1u thu\u1ed1c gi\u1ea3m \u0111au nh\u01b0 acetaminophen: Acetaminophen, d\u00f9 ph\u1ed5 bi\u1ebfn, l\u1ea1i l\u00e0 th\u1ee7 ph\u1ea1m g\u00e2y t\u1ed5n th\u01b0\u01a1ng gan c\u1ea5p t\u00ednh khi l\u1ea1m d\u1ee5ng, d\u1eabn \u0111\u1ebfn t\u0103ng men gan \u0111\u1ed9t ng\u1ed9t v\u00e0 th\u1eadm ch\u00ed suy gan. V\u1edbi kinh nghi\u1ec7m l\u00e2m s\u00e0ng, t\u00f4i nh\u1ea5n m\u1ea1nh vi\u1ec7c tu\u00e2n th\u1ee7 li\u1ec1u l\u01b0\u1ee3ng d\u01b0\u1edbi 4g\/ng\u00e0y v\u00e0 tr\u00e1nh k\u1ebft h\u1ee3p v\u1edbi r\u01b0\u1ee3u. Nghi\u00ean c\u1ee9u v\u1ec1 suy gan c\u1ea5p cho th\u1ea5y c\u00e1c tr\u01b0\u1eddng h\u1ee3p ti\u1ebfn tri\u1ec3n ch\u1eadm th\u01b0\u1eddng do thu\u1ed1c g\u00e2y ra, c\u00f3 th\u1ec3 nh\u1ea7m l\u1eabn v\u1edbi b\u1ec7nh gan m\u1ea1n t\u00ednh, nh\u01b0ng ho\u00e0n to\u00e0n tr\u00e1nh \u0111\u01b0\u1ee3c.<\/p>\n\n\n\n

5.        Nhi\u1ec5m virus vi\u00eam gan B: Virus vi\u00eam gan B (HBV) l\u00e2y lan qua \u0111\u01b0\u1eddng m\u00e1u ho\u1eb7c t\u00ecnh d\u1ee5c, g\u00e2y vi\u00eam gan m\u1ea1n t\u00ednh v\u00e0 t\u0103ng men gan, nh\u01b0ng vaccine \u0111\u00e3 thay \u0111\u1ed5i c\u1ee5c di\u1ec7n. Ti\u00eam vaccine gi\u00fap ng\u0103n ng\u1eeba h\u00e0ng tri\u1ec7u ca b\u1ec7nh, nh\u1ea5n m\u1ea1nh t\u1ea7m quan tr\u1ecdng c\u1ee7a ti\u00eam ch\u1ee7ng to\u00e0n d\u00e2n. C\u00e1c analog nucleoside m\u1ea1nh c\u00f3 th\u1ec3 thay th\u1ebf immunoglobulin \u0111\u1ec3 ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t sau gh\u00e9p gan. <\/p>\n\n\n\n

B\u1ec7nh vi\u1ec7n K\u00edng\u2019s College Hospital<\/figcaption><\/figure>\n\n\n\n

6.        Nhi\u1ec5m virus vi\u00eam gan C: T\u01b0\u01a1ng t\u1ef1 HBV, virus vi\u00eam gan C (HCV) g\u00e2y t\u0103ng men gan m\u1ea1n t\u00ednh qua \u0111\u01b0\u1eddng m\u00e1u, nh\u01b0ng c\u00e1c h\u00e0nh vi an to\u00e0n nh\u01b0 s\u1eed d\u1ee5ng kim s\u1ea1ch v\u00e0 s\u00e0ng l\u1ecdc m\u00e1u c\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf r\u1ee7i ro.  \u0110i\u1ec1u tr\u1ecb nh\u1edd thu\u1ed1c kh\u00e1ng virus tr\u1ef1c ti\u1ebfp c\u00f3 th\u1ec3 kh\u1ecfi b\u00eanh vi\u00eam gan C ho\u00e0n to\u00e0n, nh\u01b0ng ph\u00f2ng ng\u1eeba v\u1eabn l\u00e0 \u01b0u ti\u00ean. Ph\u00e2n t\u00edch g\u00e1nh n\u1eb7ng x\u01a1 gan to\u00e0n c\u1ea7u cho th\u1ea5y HCV l\u00e0 nguy\u00ean nh\u00e2n l\u1edbn, nh\u01b0ng c\u00f3 th\u1ec3 ph\u00f2ng ng\u1eeba th\u00f4ng qua gi\u00e1o d\u1ee5c v\u00e0 ki\u1ec3m so\u00e1t. <\/p>\n\n\n\n

7.        Ti\u1ebfp x\u00fac v\u1edbi h\u00f3a ch\u1ea5t \u0111\u1ed9c h\u1ea1i: C\u00e1c h\u00f3a ch\u1ea5t c\u00f4ng nghi\u1ec7p nh\u01b0 dung m\u00f4i ho\u1eb7c thu\u1ed1c tr\u1eeb s\u00e2u c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng gan, t\u0103ng men gan qua c\u01a1 ch\u1ebf \u0111\u1ed9c t\u00ednh tr\u1ef1c ti\u1ebfp. Kinh nghi\u1ec7m c\u1ee7a t\u00f4i v\u1edbi b\u1ec7nh nh\u00e2n lao \u0111\u1ed9ng cho th\u1ea5y b\u1ea3o h\u1ed9 lao \u0111\u1ed9ng l\u00e0 ch\u00eca kh\u00f3a, tr\u00e1nh ti\u1ebfp x\u00fac kh\u00f4ng c\u1ea7n thi\u1ebft. <\/p>\n\n\n\n

8.        H\u00fat thu\u1ed1c l\u00e1: H\u00fat thu\u1ed1c kh\u00f4ng ch\u1ec9 h\u1ea1i ph\u1ed5i m\u00e0 c\u00f2n l\u00e0m tr\u1ea7m tr\u1ecdng h\u00f3a t\u1ed5n th\u01b0\u01a1ng gan, t\u0103ng men gan qua stress oxy h\u00f3a v\u00e0 vi\u00eam. T\u00f4i th\u01b0\u1eddng khuy\u00ean b\u1ec7nh nh\u00e2n b\u1ecf thu\u1ed1c \u0111\u1ec3 gi\u1ea3m nguy c\u01a1, v\u00ec gan v\u1ed1n \u0111\u00e3 ch\u1ecbu g\u00e1nh n\u1eb7ng t\u1eeb c\u00e1c y\u1ebfu t\u1ed1 kh\u00e1c. C\u00e1c nghi\u00ean c\u1ee9u gi\u00e1n ti\u1ebfp v\u1ec1 b\u1ec7nh gan li\u00ean quan \u0111\u1ebfn vi\u00eam h\u1ec7 th\u1ed1ng cho th\u1ea5y CRP t\u0103ng \u1edf x\u01a1 gan, v\u00e0 h\u00fat thu\u1ed1c g\u00f3p ph\u1ea7n, nh\u01b0ng cai nghi\u1ec7n l\u00e0 bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba hi\u1ec7u qu\u1ea3. <\/p>\n\n\n\n

9.        S\u1eed d\u1ee5ng th\u1ea3o d\u01b0\u1ee3c v\u00e0 th\u1ef1c ph\u1ea9m b\u1ed5 sung kh\u00f4ng ki\u1ec3m so\u00e1t: Nhi\u1ec1u th\u1ea3o d\u01b0\u1ee3c \u0111\u01b0\u1ee3c cho l\u00e0 “t\u1ef1 nhi\u00ean” l\u1ea1i ch\u1ee9a \u0111\u1ed9c t\u1ed1 g\u00e2y t\u0103ng men gan, nh\u01b0 kava ho\u1eb7c green tea extract \u1edf li\u1ec1u cao. V\u1edbi kinh nghi\u1ec7m, t\u00f4i c\u1ea3nh b\u00e1o b\u1ec7nh nh\u00e2n ki\u1ec3m tra ngu\u1ed3n g\u1ed1c v\u00e0 tham kh\u1ea3o b\u00e1c s\u0129. <\/p>\n\n\n\n

10.  L\u1ed1i s\u1ed1ng \u00edt v\u1eadn \u0111\u1ed9ng: Thi\u1ebfu t\u1eadp luy\u1ec7n d\u1eabn \u0111\u1ebfn t\u00edch t\u1ee5 m\u1ee1 gan, t\u0103ng men gan qua c\u01a1 ch\u1ebf kh\u00e1ng insulin. T\u00f4i lu\u00f4n khuy\u1ebfn kh\u00edch 150 ph\u00fat t\u1eadp luy\u1ec7n h\u00e0ng tu\u1ea7n, v\u00ec gan c\u1ea7n s\u1ef1 k\u00edch th\u00edch \u0111\u1ec3 trao \u0111\u1ed5i ch\u1ea5t hi\u1ec7u qu\u1ea3. Li\u00ean quan \u0111\u1ebfn NAFLD, nghi\u00ean c\u1ee9u cho th\u1ea5y probiotic v\u00e0 thay \u0111\u1ed5i l\u1ed1i s\u1ed1ng c\u00f3 th\u1ec3 ch\u1ed1ng l\u1ea1i t\u00edch t\u1ee5 m\u1ee1, nh\u1ea5n m\u1ea1nh v\u1eadn \u0111\u1ed9ng l\u00e0 y\u1ebfu t\u1ed1 ph\u00f2ng ng\u1eeba c\u1ed1t l\u00f5i.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\ud83d\udc68\u200d\u2695\ufe0f ThS.BS Tr\u1ea7n H\u1eefu Hi\u1ec1n \u2022 T\u1ed1t nghi\u1ec7p b\u1eb1ng DIU \u0110\u1ea1i h\u1ecdc Corse \u2013 C\u1ed9ng h\u00f2a Ph\u00e1p – Tu nghi\u1ec7p t\u1ea1i b\u1ec7nh vi\u1ec7n King\u2019s College Hospital Lu\u00e2n \u0110\u00f4n Anh Qu\u1ed1c…<\/p>\n","protected":false},"author":1,"featured_media":3358,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[117,67,84],"jetpack_featured_media_url":"https:\/\/hienbacsi.com\/wp-content\/uploads\/2025\/08\/img_0003.jpg","_links":{"self":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3359"}],"collection":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/comments?post=3359"}],"version-history":[{"count":1,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3359\/revisions"}],"predecessor-version":[{"id":3360,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/posts\/3359\/revisions\/3360"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/media\/3358"}],"wp:attachment":[{"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/media?parent=3359"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/categories?post=3359"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hienbacsi.com\/index.php\/wp-json\/wp\/v2\/tags?post=3359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}